Searchable abstracts of presentations at key conferences in endocrinology

ea0056p927 | Female Reproduction | ECE2018

Disentangling polycystic ovary syndrome (PCOS) components by liquid-chromatography – tandem mass spectrometry (LC-MS/MS) steroid profiling

Fanelli Flaminia , Mezzullo Marco , Zanotti Laura , Fazzini Alessia , Mastroroberto Marianna , Morselli-Labate Antonio Maria , Pagotto Uberto , Pasquali Renato , Gambineri Alessandra

Introduction: Clinical and laboratory hyperandrogenisms indistinctly contribute to PCOS diagnosis; however, they differ in hormonal and metabolic correlates and require proper therapeutic strategies. Circulating biomarkers of hirsutism were not identified so far, with elevated testosterone being observed only in half of hirsute patients. Reasons for such inconsistencies possibly relies in previously used immunoassays, nowadays recognized as not adequate because of poor reliabi...